Study of Serum Gremlin-1, Galectin-3, and Oxyntomodulin in Women with Breast Cancer
Aya J. Mohammed, Entedhar R. Sarhat
The study involved measuring the concentration levels of Gremlin-1, Galectin-3, and oxyntomodulin in the serum of women with breast cancer. It included 60 samples from women with breast cancer and 30 samples from healthy individuals. The results showed that the levels of Gremlin-1 and Galectin-3 are elevated in women with breast cancer, with significant differences with P ≤ 0.0003 and P ≤ 0.0004, respectively. Meanwhile, the level of oxyntomodulin is decreased in women with breast cancer compared to the control group, with significant differences (P ≤ 0.007). Conclusion: The study revealed that the concentration levels of Gremlin-1 and Galectin-3 are significantly elevated in women with breast cancer compared to healthy individuals, while the level of oxyntomodulin is decreased. These findings suggest that these biomarkers may have potential as diagnostic markers for breast cancer. Further research is needed to determine the specific roles of these biomarkers in breast cancer development and progression and to explore their potential as targets for treatment. Overall, this study highlights the importance of biomarker analysis in improving our understanding and management of breast cancer.
Keywords: Breast cancer, Gremlin-1, Galectin-3, Oxyntomodulin
