Recovery from Sevoflurane Anesthesia: A Comparism with Isoflurane Anesthesia in pediatric undergo tonsillectomy with or without adenoidectomy under general anesthesia
Zainab M.jaafar M.saeed Alkahteeb, Jaafar Hameed Mahboba,
Zainab Fadhel Mohammed
Isoflurane and sevoflurane are widely used anesthetics in pediatric anesthesia. Adverse effect including postoperative nausea and vomiting are common. Prolonged recovery time and emergency time are also troubling anesthesiologists, so in this study, we aimed at performing a comprehensive-study concerning the emergence and recovery characteristics of these inhaled anesthetic in tonsillectomy and adenoidectomy pediatric patients.This study is designed to compare recovery in patients receiving sevoflurane or isoflurane for maintenance in pediatric patients undergo tonsillectomy with or without adenoidectomy under general anesthesia. A randomized, blind clinical trial 60 patients, 30 patients in sevoflurane group and 30 patients in isoflurane group , comparing recovery in pediatric patients with American Society Anaesthiologist I-II between (5-15years), were planned to undergo tonsillectomy with or without adenoidectomy duration 45 minute to 1 hour, under general anesthesia, Induction with propofol and rocuronium with sevoflurane and isoflurane for maintenance, assessment and monitoring by steward score Among the studied groups revealed a significant more frequent laryngospasm in Sevoflurane group, compared to the Isoflurane group, and significantly longer mean time from switching off inhalational agent to reversal agent in Sevoflurane than Isoflurane group conversely, the differences in the times at the subsequent three check points) were statistically insignificant. The scores statistically in significant at the subsequent check points, No significant variation in the incidence of nausea and vomiting, the pulse rate, respiratory rate, or oxygen saturation rate between both groups at different time of assessment, in all comparisons, We concluded that Isoflurane is a safe alternative to sevoflurane for pediatric surgery, less complication, smoother recovery Sevoflurane group had more side effects (agitation, Laryngeal spasm, faster requirement for analgesia, prolong recovery. Awakening time was surprisingly slower with sevoflurane.
Keywords: Isoflurane, Sevoflurane, Maintenance, Recovery
